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Low Dose Naltrexone

Low Dose Naltrexone

Naltrexone itself was approved by FDA in 1984 in a 50mg dose. Used to treat a person in an overdose or drug abuse situation by blocking the reception of the opioid hormones. Doctors have now begun using much lower doses for purposes of normalizing our immune system as well as inflammatory and neurological disorders. LDN boosts the immune system, activating the body’s own natural defenses. How low dose Naltrexone works has many theories in reality it reduces cell division and binds to the opioid growth factors. All agree that normal regulation of the division of cells is a good thing. When cell division gets out of control we tend to call it cancer and/ or other names. That’s when doctors and patients want a method to return the cell division to normal. Experts say eight months of therapy is required to see maximum benefit although most patients start noticing a difference in a few weeks.

This list represents just a few of many listed conditions that have been treated with LDN:

  • Alzheimer’s disease
  • Arthritis
  • Chronic fatigue
  • Depression
  • Fibromyalgia
  • Parkinson’s disease
  • Psoriasis/ Eczema
  • Systemic Lupus


The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain. Feb 2014.

Low Dose Naltrexone | Systems Neuroscience and Pain Lab | Stanford Medicine. 2009.

Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndrome. 2015.

Pennsylvania State University College of Medicine; LDN: Tricking the body to heal itself. Sept 2011.

Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study. May 2009.

Low-dose naltrexone therapy improves active Crohn’s disease. Jan 2007.

Pilot trial of low‐dose naltrexone and quality of life in multiple sclerosis. Aug 2010.