A leading compounding pharmacy specializing in Mold Toxicity, CIRS, Biotoxin Illness, Lyme Disease, Sinus and Allergy/ENT, Dermatology and Aesthetics.

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EDTA Nasal Spray | Nasal Solution

EDTA Nasal Spray | EDTA Nasal Solution

0.25%, 0.5%, or 1% Nasal Spray
15mg/2ml Solution for Atomization or Nasal Rinse
(Custom dosing available upon prescriber’s request)

EDTA or edetate disodium is a chelating agent that aids in the destruction of bacterial biofilm caused by mold exposure. Leading mold experts, like Dr. Ritchie Shoemaker, have found compounded EDTA to be beneficial in the treatment of Chronic Inflammatory Response Syndrome (CIRS) and other mold and biotoxin-related illnesses. The biofilm that forms as a result of mold toxicity can be extremely resistant to antimicrobial and antifungal agents and will continue to harbor bacteria, mold, and fungus if treated with topical antibiotics or antifungals alone. Therefore, a chelating agent like EDTA has been recommended for the treatment of mold and biotoxin illnesses by leading doctors in the field and is described as an important component in the protocols established by Dr. Ritchie Shoemaker, Dr. Joseph Brewer, and Dr. Neil Nathan.

Forte Rx Compounding Pharmacy specializes in making custom compounded treatments for sinus, mold, and biotoxin illness patients including EDTA nasal spray, 100% Pure Cholestyramine Resin (CSM), SynapsinⓇ nasal spray, Itraconazole nasal spray, Amphotericin B nasal spray, and BEG and BEG-I nasal sprays and more. Forte Rx is owned and operated by Dr. Haleh Khatami Pharm.D., who has been nationally recognized for her expertise in the field of sinus, mold, and biotoxin illnesses. At Forte Rx Compounding Pharmacy, the health and safety of all our patients is our number one priority. For this reason, we only source our ingredients from trusted vendors who verify and test every lot and provide us with valid Certificates of Analysis.

EDTA Applications

EDTA Nasal Spray
0.25%, 0.5%, or 1%

EDTA solution can be dispensed in a nasal spray with a metered dose pump that releases the accurate prescribed quantity of the EDTA solution into a patient’s sinus cavity.

Atomized/Nasal Rinse EDTA
15mg/2ml Solution for Atomization or Nasal Rinse

We offer EDTA solutions in a portable Rhino Clear Sprint atomizer device. Rhino Clear Sprint sprays the medication as a fine mist into the sinus cavity in a non-invasive way. Rhino Clear electronic atomizer can be included in your order of EDTA with a prescription from your prescriber.

EDTA & Xylitol

Xylitol has been recommended by leading Ear, Nose, and Throat (ENT) surgeons and physicians in treating respiratory infections due to its ability to clear nasal passages. Xylitol is an organic sugar alcohol naturally occurring in fruit and hardwood trees. Xylitol is often associated with being an alternative sweetener for diabetic patients due to its low glycemic index. When used alongside EDTA, xylitol enhances the body’s ability to fight off symptoms of chronic rhinosinusitis. Xylitol is generally well-tolerated by the body and produces little to no side effects.[1]

EDTA & Argentyn 23

Argentyn 23Ⓡ is an over-the-counter 23ppm hydrosol silver dietary supplement often used to support the immune system. Recently, doctors have been recommending the use of 23 ppm hydrosol silver along with an EDTA nasal spray.
When a prescriber recommends Argentyn 23Ⓡ to be included in their patient’s order of EDTA, we will include Argentyn 23Ⓡ in its own separate spray bottle along with the EDTA nasal spray.

Please contact our clinical department today at (805) 427-9053 and ask to speak with one of our expert mold, biotoxin illness, sinus, and Lyme Disease clinical pharmacists about EDTA Nasal Spray.

Percival S.L., Salisbury AM. (2017) The Efficacy of Tetrasodium EDTA on Biofilms. In: Donelli G. (eds) Advances in Microbiology, Infectious Diseases and Public Health. Advances in Experimental Medicine and Biology, vol 1057. Springer, Cham. https://doi.org/10.1007/5584_2017_134

Dr. Shoemaker’s 11- Step Treatment Protocol for Biotoxin Illnesses https://www.wondermakers.com/Portals/0/11-Step%20Treatment%20for%20Biotoxin%20Illness.pdf

Kite, P., Eastwood, K., Sugden, S., & Percival, S. L. (2004). Use of in vivo-generated biofilms from hemodialysis catheters to test the efficacy of a novel antimicrobial catheter lock for biofilm eradication in vitro. Journal of Clinical Microbiology, 42(7), 3073–3076. https://doi.org/10.1128/jcm.42.7.3073-3076.2004

The use of Xylitol nasal irrigation in the treatment of CRS

Lin, L., Tang, X., Wei, J., Dai, F., & Sun, G. (2017). Xylitol nasal irrigation in the treatment of chronic rhinosinusitis. American Journal of Otolaryngology, 38(4), 383–389. https://doi.org/10.1016/j.amjoto.2017.03.006

Ur-Rehman S, Mushtaq Z, Zahoor T, Jamil A, Murtaza MA. Xylitol: a review on bioproduction, application, health benefits, and related safety issues. Crit Rev Food Sci Nutr. 2015;55(11):1514-28. doi: 10.1080/10408398.2012.702288. PMID: 24915309.

Weissman JD, Fernandez F, Hwang PH. Xylitol nasal irrigation in the management of chronic rhinosinusitis: a pilot study. Laryngoscope. 2011 Nov;121(11):2468-72. doi: 10.1002/lary.22176. Epub 2011 Oct 12. Erratum in: Laryngoscope. 2012 Nov;122(11):2611. PMID: 21994147.

[1]Salli, K., Lehtinen, M. J., Tiihonen, K., & Ouwehand, A. C. (2019). Xylitol’s Health Benefits beyond Dental Health: A Comprehensive Review. Nutrients, 11(8), 1813. https://doi.org/10.3390/nu11081813